Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577793 | 0.86 | ALDH1A1 (0.52) | KDM4EPOLBALDH1A1LMNACYP1A2 | |
| SCHEMBL17705862 | 0.81 | ALDH1A1 (0.52) | KDM4EPOLBALDH1A1LMNAESR1 | |
| SCHEMBL8578537 | 0.79 | ALDH1A1 (0.44) | KDM4EPOLBALDH1A1LMNACYP1A2 | |
| SCHEMBL9461048 | 0.79 | ALDH1A1 (0.53) | KDM4EPOLBALDH1A1LMNACYP1A2 | |
| SCHEMBL8404026 | 0.77 | ALDH1A1 (0.64) | KDM4EPOLBALDH1A1LMNACYP1A2 | |
| SCHEMBL8571437 | 0.77 | ALDH1A1 (0.48) | KDM4EPOLBALDH1A1LMNACYP1A2 | |
| SCHEMBL17253632 | 0.75 | ADORA3 (0.45) | KDM4EPOLBALDH1A1ESR1MAPT | |
| SCHEMBL4768834 | 0.75 | HTR4 (0.39) | KDM4EALDH1A1LMNACYP1A2ESR1 | |
| SCHEMBL8406394 | 0.74 | TDP1 (0.51) | POLBALDH1A1LMNATSHRSLC6A2 | |
| SCHEMBL10365849 | 0.74 | NPSR1 (0.65) | ALDH1A1CYP1A2EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869667-A | Process for preparing 2- pyrimidinecarboxylates | LONZA AG (CH) | 1999-02-09 | — | — | US | disclosed |
| WO-1998018789-A1 | PROCESS FOR THE PREPARATION OF PHTALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-07 | — | — | WO | disclosed |