Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 13/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 11/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839910 | 0.96 | AGTR1 (0.37) | AGTR1AGTR2MME | |
| SCHEMBL840212 | 0.93 | AGTR1 (0.36) | AGTR1AGTR2MME | |
| SCHEMBL839142 | 0.93 | MME (0.40) | AGTR1AGTR2MME | |
| SCHEMBL839141 | 0.93 | MME (0.40) | AGTR1AGTR2MME | |
| SCHEMBL838701 | 0.90 | AGTR1 (0.36) | AGTR1AGTR2MME | |
| SCHEMBL838700 | 0.90 | AGTR1 (0.36) | AGTR1AGTR2MME | |
| SCHEMBL839968 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2MME | |
| SCHEMBL839967 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2MME | |
| SCHEMBL839509 | 0.89 | AGTR1 (0.43) | AGTR1AGTR2MME | |
| SCHEMBL839805 | 0.88 | AGTR1 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143298-B2 | Dual-acting antihypertensive agents | THERAVANCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |