Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 12/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 11/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840591 | 0.93 | AGTR1 (0.37) | AGTR1AGTR2MME | |
| SCHEMBL840037 | 0.92 | MME (0.41) | AGTR1AGTR2MME | |
| SCHEMBL840038 | 0.92 | MME (0.41) | AGTR1AGTR2MME | |
| SCHEMBL840592 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2MME | |
| SCHEMBL840593 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2MME | |
| SCHEMBL839970 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2MME | |
| SCHEMBL839910 | 0.89 | AGTR1 (0.37) | AGTR1AGTR2MME | |
| SCHEMBL839146 | 0.89 | AGTR1 (0.37) | AGTR1AGTR2MME | |
| SCHEMBL839145 | 0.89 | AGTR1 (0.37) | AGTR1AGTR2MME | |
| SCHEMBL840471 | 0.87 | AGTR1 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143298-B2 | Dual-acting antihypertensive agents | THERAVANCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |