SCHEMBL8406882

SCHEMBL8406882

CCCCCCCCCn1nnc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 8/20 1.00
CYP4Z1 Q86W10 5/20 0.57
NPC1 O15118 1/20 0.57
MAPT P10636 1/20 0.57
RAB9A P51151 1/20 0.57
HCAR3 P49019 1/20 0.56
GLA P06280 1/20 0.55
TSHR P16473 1/20 0.55
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
EGLN3 Q9H6Z9 1/20 0.54
P2RX7 Q99572 1/20 0.52
GRM2 Q14416 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445452 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL535676 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL27617630 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8664499 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL461412 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL7549692 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8633983 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL9637546 0.98 SLC9A1 (0.97) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL462848 0.98 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL1834794 0.93 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712834-B1 High oleic polyol esters, compositions and lubricants functional fluids and greases containing the same LUBRIZOL CORP (US) 1999-07-14 EP claimed
US-5773391-A VEGETABLE OIL, ANTIOXIDANT, METAL DEACTIVATOR OF BENZOTRIAZOLE AND HYDROXYL GROUPS THE LUBRIZOL CORPORATION (US) 1998-06-30 US claimed
EP-0712834-A1 High oleic polyol esters, compositions and lubricants functional fluids and greases containing the same THE LUBRIZOL CORPORATION (US) 1996-05-22 EP claimed
US-4166837-A FUSED N-ALKYL-TRIAZOLE KING INDUSTRIES, INC. (US) 1979-09-04 US claimed
US-4255395-A Solvent-extraction process for recovery and separation of metal values KING INDUSTRIES, INC. (US) 1981-03-10 US disclosed
US-4166837-A FUSED N-ALKYL-TRIAZOLE KING INDUSTRIES, INC. (US) 1979-09-04 US disclosed