SCHEMBL445452

SCHEMBL445452

CCCCCCCCn1nnc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 8/20 1.00
CYP4Z1 Q86W10 5/20 0.57
NPC1 O15118 1/20 0.57
MAPT P10636 1/20 0.57
RAB9A P51151 1/20 0.57
HCAR3 P49019 1/20 0.56
GLA P06280 1/20 0.55
TSHR P16473 1/20 0.55
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
EGLN3 Q9H6Z9 1/20 0.54
P2RX7 Q99572 1/20 0.52
GRM2 Q14416 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535676 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL27617630 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8664499 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL461412 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8406882 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL7549692 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8633983 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL9637546 0.98 SLC9A1 (0.97) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL462848 0.98 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL1834794 0.93 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963467-B1 Process for the preparation of a hydraulic fluid composition COUNCIL SCIENT IND RES (IN) 2014-03-26 EP claimed
US-8658575-B2 Composition of insulating fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-02-25 US claimed
US-20130277825-A1 Method for Preventing Corrosion of Copper-Aluminum Intermetallic Compounds TEXAS INSTRUMENTS INCORPORATED (US) 2013-10-24 US claimed
US-8557754-B2 Composition of biodegradable gear oil COUNSEL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-10-15 US claimed
EP-2601245-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF Biofilm IP, LLC (US) 2013-06-12 EP claimed
WO-2012018403-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM IP, LLC (US) 2012-02-09 WO claimed
US-8034751-B2 Composition of hydraulic fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-10-11 US claimed
US-20110207638-A1 COMPOSITION OF BIODEGRADABLE GEAR OIL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-08-25 US claimed
US-7825077-B2 Composition of lubricating oil for two stroke gasoline engine and process for the preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2010-11-02 US claimed
EP-1969607-B1 A COMPOSITION OF INSULATING FLUID AND PROCESS FOR THE PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2010-03-10 EP claimed
US-20070135318-A1 Composition of lubricating oil for two stroke gasoline engine and process for the preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2007-06-14 US claimed
US-20070060486-A1 Composition of hydraulic fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-03-15 US claimed
US-20070060484-A1 Composition of insulating fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-03-15 US claimed
EP-0397454-A1 Higher alkylbenzotriazoles as copper and copper alloy corrosion inhibitors CALGON CORPORATION (US) 1990-11-14 EP claimed
CN-122095059-A Contains high content of C9Lubricant composition of di-substituted diphenylamine antioxidant 2026-05-26 CN disclosed
WO-2026099357-A1 LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (GB) 2026-05-15 WO disclosed
US-20260132352-A1 LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LTD (GB) 2026-05-14 US disclosed
EP-0141839-A1 PHOSPHORUS-CONTAINING METAL SALTS/SULFURIZED PHENATE COMPOSITIONS/AROMATIC SUBSTITUTED TRIAZOLES, CONCENTRATES, AND FUNCTIONAL FLUIDS CONTAINING SAME. LUBRIZOL CORP (US) 1985-05-22 EP disclosed
WO-1984004322-A1 PHOSPHORUS-CONTAINING METAL SALTS/SULFURIZED PHENATE COMPOSITIONS/AROMATIC SUBSTITUTED TRIAZOLES, CONCENTRATES, AND FUNCTIONAL FLUIDS CONTAINING SAME LUBRIZOL CORP (US) 1984-11-08 WO disclosed
US-4466894-A Phosphorus-containing metal salts/sulfurized phenate compositions/aromatic substituted triazoles, concentrates, and functional fluids containing same THE LUBRIZOL CORPORATION (US) 1984-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132352-A1 LUBRICATING OIL COMPOSITIONS SFN, DGKG, TAF1 SLC9A1 3322/4885CYP4Z1 4180/4885NPC1 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.