SCHEMBL535676

SCHEMBL535676

CCCCCCCCCCCCCCCCCCn1nnc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 8/20 1.00
CYP4Z1 Q86W10 5/20 0.57
NPC1 O15118 1/20 0.57
MAPT P10636 1/20 0.57
RAB9A P51151 1/20 0.57
HCAR3 P49019 1/20 0.56
GLA P06280 1/20 0.55
TSHR P16473 1/20 0.55
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
EGLN3 Q9H6Z9 1/20 0.54
P2RX7 Q99572 1/20 0.52
GRM2 Q14416 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445452 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL27617630 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8664499 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL461412 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8406882 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL7549692 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL8633983 1.00 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL9637546 0.98 SLC9A1 (0.97) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL462848 0.98 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A
SCHEMBL1834794 0.93 SLC9A1 (1.00) SLC9A1CYP4Z1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10822359-B2 Benzotriazole derivative, preparation process and the use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-11-03 US disclosed
US-20190106446-A1 BENZOTRIAZOLE DERIVATIVE, PREPARATION PROCESS AND THE USE THEREOF RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2019-04-11 US disclosed
EP-1952918-B1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO (JP) 2013-05-22 EP disclosed
US-8440110-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG CO., LTD. (JP) 2013-05-14 US disclosed
EP-1990377-B1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KK (JP) 2012-02-08 EP disclosed
CN-101384674-B Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2011-12-28 CN disclosed
US-7998266-B2 Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation containing said colored metallic pigment TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2011-08-16 US disclosed
US-20110175040-A1 METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO., LTD. (JP) 2011-07-21 US disclosed
US-7981327-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG. CO. LTD. (JP) 2011-07-19 US disclosed
US-20090258202-A1 Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) 2009-10-15 US disclosed
CN-101384674-A Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment TOYO ALUMINIUM KK (JP) 2009-03-11 CN disclosed
US-20090017082-A1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2009-01-15 US disclosed
EP-1990377-A1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION COMPRISING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2008-11-12 EP disclosed
EP-1952918-A1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM Toyo Ink Mfg. Co., Ltd (JP) 2008-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10822359-B2 Benzotriazole derivative, preparation process and the use thereof SULT1A1, TAF5, TAF1 SLC9A1 4499/4885CYP4Z1 493/4885NPC1 4319/4885
US-20190106446-A1 BENZOTRIAZOLE DERIVATIVE, PREPARATION PROCESS AND THE USE THEREOF SULT1A1, TAF5, TAF1 SLC9A1 4499/4885CYP4Z1 493/4885NPC1 4319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.