Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863340 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8410466 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL8949202 | 0.75 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL8949010 | 0.74 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL8949136 | 0.73 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL8949182 | 0.73 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL8410417 | 0.72 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8407358 | 0.71 | SMN1; SMN2 (0.54) | ITGB3ITGA2B | |
| SCHEMBL8949282 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL24492532 | 0.70 | ALDH1A1 (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |