SCHEMBL8407382

SCHEMBL8407382

O=C(/C=C/c1ccccc1)OC(=O)c1ccccc1O.[Zn]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
CYP2C19 P33261 2/20 0.61
BCHE P06276 1/20 0.61
MAOB P27338 7/20 0.55
RAB9A P51151 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
KCNH2 Q12809 1/20 0.54
NPC1 O15118 1/20 0.54
MAOA P21397 5/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX12 P18054 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11318439 0.89 GLA (0.55) MAPTCYP2C19BCHEMAOBRAB9A
SCHEMBL14802090 0.85 MAPT (0.51) MAPTCYP2C19BCHEMAOBRAB9A
SCHEMBL5758102 0.84 MAPT (0.71) MAPTCYP2C19BCHEMAOBRAB9A
SCHEMBL7299840 0.82 HPGD (0.51) MAPTCYP2C19BCHEMAOBKDM4E
SCHEMBL2849418 0.81 MAPT (0.64) MAPTCYP2C19BCHERAB9AKDM4E
SCHEMBL2849416 0.81 MAPT (0.64) MAPTCYP2C19BCHERAB9AKDM4E
SCHEMBL1721570 0.80 MAPT (0.56) MAPTBCHEMAOBRAB9AMEN1
SCHEMBL775716 0.79 MAPT (0.64) MAPTBCHEMAOBRAB9AMEN1
SCHEMBL21803794 0.79 MAPT (0.64) MAPTBCHEMAOBRAB9AMEN1
SCHEMBL9247555 0.79 MAPT (0.64) MAPTBCHEMAOBRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001520-A CONTAINS A CHARGE GENERATING LAYER AND A CHARGE TRANSPORTING LAYER WHICH CONTAINS A ZINC CARBOXYLATE WITH ALKENYL AND AROMATIC ACID GROUPS FUJI ELECTRIC CO., LTD. (JP) 1999-12-14 US claimed
US-6001520-A CONTAINS A CHARGE GENERATING LAYER AND A CHARGE TRANSPORTING LAYER WHICH CONTAINS A ZINC CARBOXYLATE WITH ALKENYL AND AROMATIC ACID GROUPS FUJI ELECTRIC CO., LTD. (JP) 1999-12-14 US disclosed