Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849418 | 1.00 | MAPT (0.64) | MAPTALDH1A1HSD17B10CFTRRAB9A | |
| SCHEMBL21571614 | 0.90 | MAPT (0.51) | MAPTALDH1A1HSD17B10CFTRRAB9A | |
| SCHEMBL11318439 | 0.89 | GLA (0.55) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14801793 | 0.84 | GUSB (0.52) | MAPTALDH1A1HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL23357451 | 0.84 | ALDH1A1 (0.51) | MAPTALDH1A1HSD17B10CFTRRAB9A | |
| SCHEMBL28259523 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1HSD17B10CFTRRAB9A | |
| SCHEMBL14802090 | 0.82 | MAPT (0.51) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8407382 | 0.81 | MAPT (0.61) | MAPTALDH1A1HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL28839863 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1HSD17B10CFTRRAB9A | |
| SCHEMBL7557914 | 0.81 | BCHE (0.53) | MAPTALDH1A1HSD17B10CFTRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280441-B2 | Host cells and methods for producing cinnamoyl anthranilate and analogs thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-07 | — | — | US | claimed |
| US-20140072584-A1 | NOVEL PHARMACEUTICAL USE OF BENZOIC ACID DERIVATIVES | LI, YINGJI (CN) | 2014-03-13 | — | — | US | claimed |
| US-20130078683-A1 | Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-28 | — | — | US | claimed |
| US-20100130497-A1 | Therapeutic Compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-05-27 | — | — | US | claimed |
| CN-101600683-A | Therapeutic compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2009-12-09 | — | — | CN | claimed |
| EP-2035369-A1 | THERAPEUTIC COMPOUNDS | Fibrotech Therapeutics PTY LTD (AU) | 2009-03-18 | — | — | EP | claimed |
| WO-2008003141-A1 | THERAPEUTIC COMPOUNDS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-01-10 | — | — | WO | claimed |
| US-20230270703-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF EYE DISORDERS | OCCURX PTY LTD (AU) | 2023-08-31 | — | — | US | disclosed |
| CN-116033901-A | Compounds and methods for treating ocular disorders | 奥克尔克斯有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-4161527-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF EYE DISORDERS | OccuRx Pty Ltd (AU) | 2023-04-12 | — | — | EP | disclosed |
| US-10280441-B2 | Host cells and methods for producing cinnamoyl anthranilate and analogs thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-07 | — | — | US | disclosed |
| US-10280441-B2 | Host cells and methods for producing cinnamoyl anthranilate and analogs thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-07 | — | — | US | disclosed |
| US-10280441-B2 | Host cells and methods for producing cinnamoyl anthranilate and analogs thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-07 | — | — | US | disclosed |
| EP-2035369-A1 | THERAPEUTIC COMPOUNDS | Fibrotech Therapeutics PTY LTD (AU) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003141-A1 | THERAPEUTIC COMPOUNDS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008003141-A1 | THERAPEUTIC COMPOUNDS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-01-10 | — | — | WO | disclosed |
| CN-1713904-A | Anthranilamides and derivatives thereof as cosmetically and pharmaceutically active compounds | SYMRISE GMBH & CO KG (DE) | 2005-12-28 | — | — | CN | disclosed |
| CN-1081623-C | Benzene derivatives | TEIJIN LTD (JP) | 2002-03-27 | — | — | CN | disclosed |
| CN-1173169-A | Benzene derivatives | TEIJIN LTD (JP) | 1998-02-11 | — | — | CN | disclosed |
| US-3998974-A | Comestibles containing non-nutritive flavoring | DYNAPOL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140072584-A1 | NOVEL PHARMACEUTICAL USE OF BENZOIC ACID DERIVATIVES | NFATC1, GABRA5, GABRA6 | MAPT 4128/4885ALDH1A1 595/4885HSD17B10 753/4885 |
| US-20230270703-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF EYE DISORDERS | ALDH1A2, RBP4, RARB | MAPT 3298/4885ALDH1A1 264/4885HSD17B10 1490/4885 |
| US-20100130497-A1 | Therapeutic Compounds | NFATC1, NAT1, AADAC | MAPT 3019/4885ALDH1A1 199/4885HSD17B10 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.