SCHEMBL8407567

SCHEMBL8407567

NC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.76
CA12 O43570 3/20 0.63
CA1 P00915 3/20 0.63
CA2 P00918 3/20 0.63
CA9 Q16790 3/20 0.63
MEN1 O00255 1/20 0.62
ABL1 P00519 1/20 0.62
LMNA P02545 1/20 0.62
PKM P14618 1/20 0.62
IDE P14735 1/20 0.62
MAPK1 P28482 1/20 0.62
KMT2A Q03164 1/20 0.62
RIN1 Q13671 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
PLCD1 P51178 1/20 0.61
HLCS P50747 1/20 0.58
ITGB1 P05556 1/20 0.58
ITGA4 P13612 1/20 0.58
F2 P00734 1/20 0.58
PRSS1 P07477 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841368 1.00 TDP1 (0.76) TDP1CA12CA1CA2CA9
SCHEMBL18025829 1.00 TDP1 (0.76) TDP1CA12CA1CA2CA9
SCHEMBL31621058 1.00 TDP1 (0.76) TDP1CA12CA1CA2CA9
SCHEMBL13169001 1.00 TDP1 (0.76) TDP1CA12CA1CA2CA9
SCHEMBL19069314 1.00 TDP1 (0.76) TDP1CA12CA1CA2CA9
SCHEMBL24750115 1.00 TDP1 (0.76) TDP1CA12CA1CA2CA9
SCHEMBL8333056 0.98 TDP1 (0.73) TDP1CA12CA1CA2CA9
SCHEMBL24627775 0.97 TDP1 (0.74) TDP1CA12CA1CA2CA9
SCHEMBL18779801 0.95 TDP1 (0.78) TDP1CA12CA1CA2CA9
SCHEMBL19960973 0.94 TDP1 (0.74) TDP1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956361-B Antibodies to ticagrelor and methods of use thereof 免疫医疗有限公司 2025-06-17 CN disclosed
US-11161884-B2 Modified biotin, streptavidin mutant, and usage of them SAVID THERAPEUTICS INC. (JP) 2021-11-02 US disclosed
US-11124549-B2 2021-09-21 US disclosed
US-9694086-B2 HCV protease inhibitors and uses thereof CELGENE CAR LLC (BM) 2017-07-04 US disclosed
US-20160243249-A1 HCV PROTEASE INHIBITORS AND USES THEREOF CELGENE CAR LLC (BM) 2016-08-25 US disclosed
US-5936065-A PRODRUG AS ANTIINFLAMMATORY AGENT FOR AUTOIMMUNE DISEASES; FOR SUPPRESSING BINDING OF INFLAMMATORY CELLS TO ENDOTHELIAL CELLS THAT EXPRESS THE CS-1 PORTION OF FIBRONECTIN ON THEIR SURFACES CYTEL CORPORATION (US) 1999-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124549-B2 BTD, HLCS, BROX TDP1 4590/4885CA12 4601/4885CA1 4874/4885
US-20160243249-A1 HCV PROTEASE INHIBITORS AND USES THEREOF PEPD, CTRL, CTSC TDP1 2867/4885CA12 2068/4885CA1 3888/4885
US-11161884-B2 Modified biotin, streptavidin mutant, and usage of them BTD, HLCS, BROX TDP1 4670/4885CA12 4450/4885CA1 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.