Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407792 | 0.81 | ATM (0.48) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL8407924 | 0.76 | HPGD (0.54) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL8407994 | 0.74 | ADORA3 (0.47) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL24654511 | 0.73 | GSK3B (0.55) | GSK3BMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL8407814 | 0.71 | GAA (0.47) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL4629477 | 0.71 | DAO (0.58) | GSK3BMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL1565110 | 0.71 | MEN1 (0.43) | GSK3BMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL5805556 | 0.69 | CYP1A2 (0.49) | GSK3BMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL3523181 | 0.68 | HCAR1 (0.55) | GSK3BMEN1KMT2ALMNAGAA | |
| SCHEMBL8405032 | 0.68 | KMT2A (0.46) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673938-B1 | Purine derivatives and pharmaceutically acceptable salts thereof | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1999-07-07 | — | — | EP | disclosed |
| US-5658918-A | INHIBITING NASAL MUCOUS SECRETION | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0673938-A2 | Novel purine derivatives and pharmaceutically acceptable salts thereof | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |