SCHEMBL8407982

SCHEMBL8407982

CCc1cc(O)cc(CC)c1OCCCCOc1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.46
LTA4H P09960 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
GPR84 Q9NQS5 1/20 0.43
MAPT P10636 2/20 0.42
ABCB11 O95342 1/20 0.42
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
KCNA3 P22001 1/20 0.41
KCNA5 P22460 1/20 0.41
ALDH3A1 P30838 1/20 0.41
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
DRD3 P35462 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409417 0.97 GPR84 (0.43) NR5A1LTA4HL3MBTL1GPR84MAPT
SCHEMBL8408393 0.92 NR5A1 (0.42) NR5A1LTA4HL3MBTL1GPR84MAPT
SCHEMBL8405378 0.89 DRD2 (0.40) NR5A1LTA4HL3MBTL1GPR84MAPT
SCHEMBL8408997 0.85 NR5A1 (0.46) NR5A1LTA4HL3MBTL1GPR84MAPT
SCHEMBL8406346 0.82 NR5A1 (0.44) NR5A1LTA4HL3MBTL1GPR84MAPT
SCHEMBL8408497 0.82 GPR84 (0.43) NR5A1LTA4HL3MBTL1GPR84MAPT
SCHEMBL8408761 0.81 PPARA (0.44) NR5A1LTA4HALDH1A1MRGPRX4
SCHEMBL8408310 0.81 MRGPRX4 (0.44) NR5A1LTA4HL3MBTL1GPR84MRGPRX4
SCHEMBL8409100 0.81 ALDH3A1 (0.45) NR5A1LTA4HKCNA3KCNA5ALDH3A1
SCHEMBL8408710 0.80 HTT (0.44) L3MBTL1MAPTABCB11LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128777-C Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2003-11-26 CN disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
CN-1137265-A Dihalopropene compounds, insecticides/acaricides containing the same and intermediates for their production SUMITOMO CHEMICAL CO (JP) 1996-12-04 CN disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed