SCHEMBL8408262

SCHEMBL8408262

OCC(CO)N1CCCc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NOTUM Q6P988 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MGLL Q99685 1/20 0.46
CHRM2 P08172 4/20 0.45
CHRM4 P08173 4/20 0.45
CHRM1 P11229 4/20 0.45
CHRM3 P20309 4/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13066479 0.89 ALDH1A1 (0.50) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL7111931 0.88 KMT2A (0.50) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL22397693 0.82 MEN1 (0.50) SIGMAR1SMN1; SMN2MEN1KMT2AHTT
SCHEMBL19122068 0.82 KMT2A (0.54) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL8408270 0.79 SLC6A2 (0.48) SIGMAR1NOTUMMEN1KMT2AALDH1A1
SCHEMBL23009723 0.79 SMN1; SMN2 (0.50) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL9315735 0.79 NOTUM (0.51) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL255037 0.78 NOTUM (0.50) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL29057039 0.78 SMN1; SMN2 (0.49) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A
SCHEMBL18954412 0.77 NOTUM (0.50) SIGMAR1SMN1; SMN2NOTUMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732158-B2 Adhesive compositions HENKEL AG & CO. KGAA (DE) 2023-08-22 US disclosed
US-11732158-B2 Adhesive compositions HENKEL AG & CO. KGAA (DE) 2023-08-22 US disclosed
US-10822444-B2 Reactive resins made from renewable sources Henkel IP & Holding GmbH (DE) 2020-11-03 US disclosed
US-20200040223-A1 ADHESIVE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-02-06 US disclosed
WO-2017066539-A1 REACTIVE RESINS MADE FROM RENEWABLE SOURCES Henkel IP & Holding GmbH (DE) 2017-04-20 WO disclosed
EP-2424931-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel US IP LLC (US) 2015-03-04 EP disclosed
US-8481659-B2 Cure accelerators for anaerobic curable compositions HENKEL CORPORATION (US) 2013-07-09 US disclosed
US-8481659-B2 Cure accelerators for anaerobic curable compositions HENKEL CORPORATION (US) 2013-07-09 US disclosed
US-8362112-B2 Cure accelerators for anaerobic curable compositions HENKEL IRELAND LIMITED (IE) 2013-01-29 US disclosed
US-8362112-B2 Cure accelerators for anaerobic curable compositions HENKEL IRELAND LIMITED (IE) 2013-01-29 US disclosed
US-20120157641-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-06-21 US disclosed
US-20120157641-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-06-21 US disclosed
US-20120129994-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2012-05-24 US disclosed
US-20120129994-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2012-05-24 US disclosed
WO-2010127053-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2010-11-04 WO disclosed
WO-2010127055-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2010-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157641-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS AHCY, AHCYL1, DNMT3L SIGMAR1 4206/4885SMN1; SMN2 1184/4885NOTUM 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.