SCHEMBL840862

SCHEMBL840862

CC(C(=O)O)C1(C#N)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
MME P08473 1/20 0.32
CTSK P43235 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17294312 0.90 TP53 (0.32) ALDH1A1
SCHEMBL840305 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL3817810 0.79 ALDH1A1 (0.39) ALDH1A1
SCHEMBL9819458 0.76 ALDH1A1 (0.37) ALDH1A1
SCHEMBL10225361 0.73 ALDH1A1 (0.40) ALDH1A1
SCHEMBL8158504 0.72 MME (0.36) ALDH1A1MME
SCHEMBL10177532 0.71 ALDH1A1 (0.36) ALDH1A1
SCHEMBL2862637 0.71 KDM4E (0.32) ALDH1A1DPP4
SCHEMBL840304 0.71 ALDH1A1 (0.32) ALDH1A1DPP4
SCHEMBL9819380 0.70 CTSK (0.33) CTSKDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143443-B2 Process for preparing gabapentin ZACH SYSTEM S.P.A. (IT) 2012-03-27 US disclosed