Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410226 | 0.93 | LTA4H (0.51) | ITGB3ITGA2BGAA | |
| SCHEMBL8409280 | 0.86 | CYP2D6 (0.55) | ITGB3ITGA2BGAA | |
| SCHEMBL9568173 | 0.86 | CHRM4 (0.48) | ITGB3ITGA2BGAA | |
| SCHEMBL8949098 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8410267 | 0.85 | CHRM4 (0.48) | ITGB3ITGA2BGAA | |
| SCHEMBL8409945 | 0.84 | GAA (0.49) | GAA | |
| SCHEMBL8410297 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL8863340 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8410566 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9568119 | 0.81 | F2 (0.47) | ITGB3ITGA2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |