Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8410267 | 0.99 | CHRM4 (0.48) | CHRM4GAAPOLBDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8407510 | 0.92 | LTA4H (0.47) | CHRM4GAAPOLBDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8409952 | 0.86 | CYP2D6 (0.47) | GAAPOLBCHKA | |
| SCHEMBL8409031 | 0.86 | ITGB3 (0.55) | GAAITGB3ITGA2B | |
| SCHEMBL8714606 | 0.86 | POLB (0.49) | CHRM4POLBDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8949123 | 0.85 | ITGB3 (0.40) | CHRM4ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8408022 | 0.84 | LTA4H (0.50) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9568119 | 0.84 | F2 (0.47) | GAAITGB3ITGA2B | |
| SCHEMBL9186836 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8714443 | 0.84 | F2 (0.53) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |