Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30491037 | 0.75 | BCHE (0.73) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL5072122 | 0.75 | BCHE (0.73) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL21518001 | 0.75 | TSHR (0.58) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL298386 | 0.75 | TSHR (0.67) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL7067944 | 0.74 | TUBB4A (0.46) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL19413776 | 0.74 | TSHR (0.65) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL14216835 | 0.74 | TSHR (0.54) | TSHRBLMNPSR1BCHETYR | |
| SCHEMBL606178 | 0.73 | ACHE (0.50) | NPSR1ACHECYP2C9HSD17B10ALDH1A1 | |
| SCHEMBL1682681 | 0.72 | GAA (0.77) | TSHRBLMNPSR1BCHETYR | |
| Alcohol SCHEMBL17179872 | 0.72 | TSHR (0.63) | TSHRBLMNPSR1BCHETYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512848-B1 | Enzymatic resolution of alpha-tertiary carboxylic acid esters | GENZYME CORP (US) | 1999-07-21 | — | — | EP | claimed |