SCHEMBL606178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12776310	0.78	PPARG (0.53)	ACHECYP2C9PPARGPPARDPPARA
	SCHEMBL27665407	0.78	ACHE (0.48)	ACHETNFPDE4APDE4BPDE4C
	SCHEMBL28535986	0.77	CYP2C9 (0.52)	CYP2C9HSD17B10LMNACA2ALDH1A1
	SCHEMBL5425825	0.77	LMNA (0.42)	CYP2C9HSD17B10LMNAHIF1AMAPK1
	SCHEMBL27643933	0.76	ACHE (0.49)	ACHETNFPDE4APDE4BPDE4C
	SCHEMBL4816864	0.75	ACHE (0.58)	ACHETNFPDE4APDE4BPDE4C
	SCHEMBL28542544	0.75	PTGS2 (0.45)	CYP2C9HSD17B10LMNACYP2C19
	SCHEMBL27665575	0.74	ACHE (0.47)	ACHETNFPDE4APDE4BPDE4C
	SCHEMBL8409076	0.73	TSHR (0.55)	ACHEPDE4DCYP2C9HSD17B10ALDH1A1
	SCHEMBL1649911	0.72	ACHE (0.55)	ACHETNFPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.