Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188926 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL30771873 | 0.79 | MGAM (0.47) | ALDH1A1HPGDKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL28623257 | 0.79 | MGAM (0.47) | ALDH1A1HPGDKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL9564283 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL5296027 | 0.75 | MGAM (0.51) | HSD17B10KDM4ESMN1; SMN2KMT2ARAB9A | |
| SCHEMBL820776 | 0.75 | PDE10A (0.47) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL31073982 | 0.73 | L3MBTL1 (0.48) | ALDH1A1ALOX15KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL622397 | 0.73 | L3MBTL1 (0.48) | ALDH1A1ALOX15KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2086831 | 0.73 | L3MBTL1 (0.48) | ALDH1A1ALOX15KDM4ESMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL22973154 | 0.72 | MGAM (0.37) | ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454651-B1 | Novel platelet-aggregation inhibitors | MONSANTO CO (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5091396-A | Guanidinoalkanoylaspartylpyridine derivatives; anticoagulants | MONSANTO CO. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0454651-A2 | Novel platelet-aggregation inhibitors | MONSANTO COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-5037808-A | Indolyl platelet-aggregation inhibitors | MONSANTO CO. (US) | 1991-08-06 | — | — | US | disclosed |