Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671021 | 0.81 | AHR (0.43) | ALDH1A1HPGDKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8409107 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL340836 | 0.76 | KCNN4 (0.52) | ALDH1A1ALOX15KMT2ACYP1A2CYP2C9 | |
| SCHEMBL3188926 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL9292403 | 0.74 | KCNN4 (0.50) | ALDH1A1ALOX15KMT2ACYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL8044029 | 0.74 | KCNN4 (0.50) | ALDH1A1ALOX15KMT2ACYP1A2HIF1A | |
| Water SCHEMBL9292645 | 0.72 | CES1 (0.48) | ALDH1A1ALOX15KMT2APOLBCYP1A2 | |
| SCHEMBL9958773 | 0.72 | SCN1A (0.42) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL17184519 | 0.71 | MEN1 (0.48) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL7921071 | 0.70 | AHR (0.41) | ALDH1A1HPGDKMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574774-A1 | Substituted benzothiazolyl- and quinoxalyl methoxy-phenyl acetic acid derivatives | BAYER AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0574774-A1 | Substituted benzothiazolyl- and quinoxalyl methoxy-phenyl acetic acid derivatives | BAYER AG (DE) | 1993-12-22 | — | — | EP | disclosed |