Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.57 |
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409250 | 0.90 | ALOX5 (0.62) | ALOX5F10F2ELANE | |
| Hydrochloric Acid SCHEMBL8411350 | 0.89 | ALOX5 (0.61) | ALOX5F10F2ELANE | |
| SCHEMBL8412085 | 0.82 | ALOX5 (0.55) | ALOX5F10F2ELANE | |
| SCHEMBL8411616 | 0.81 | ALOX5 (0.55) | ALOX5F10F2ELANE | |
| SCHEMBL8408963 | 0.80 | ALOX5 (0.55) | ALOX5F10F2ELANENR3C2 | |
| SCHEMBL8783922 | 0.76 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL8413218 | 0.76 | ALOX5 (0.53) | ALOX5F10F2ELANE | |
| SCHEMBL8173880 | 0.75 | ALOX5 (0.84) | ALOX5 | |
| SCHEMBL8409241 | 0.73 | ALOX5 (0.55) | ALOX5NR3C2GRM5CYP3A4CYP2D6 | |
| SCHEMBL8172966 | 0.73 | ALOX5 (0.60) | ALOX5NR3C2GRM5MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |