SCHEMBL8409250

SCHEMBL8409250

Cc1nccn1-c1ccc(COc2cc(F)cc(NC(=O)C3CCOCC3)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.62
F10 P00742 11/20 0.49
F2 P00734 3/20 0.49
ELANE P08246 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8411350 0.99 ALOX5 (0.61) ALOX5F10F2ELANE
SCHEMBL8412085 0.92 ALOX5 (0.55) ALOX5F10F2ELANE
SCHEMBL8411616 0.91 ALOX5 (0.55) ALOX5F10F2ELANE
SCHEMBL8409291 0.90 ALOX5 (0.57) ALOX5F10F2ELANE
SCHEMBL8408963 0.89 ALOX5 (0.55) ALOX5F10F2ELANE
SCHEMBL8413218 0.84 ALOX5 (0.53) ALOX5F10F2ELANE
SCHEMBL8409058 0.82 ALOX5 (0.47) ALOX5
SCHEMBL8408804 0.81 F10 (0.53) F10F2ELANE
SCHEMBL8172966 0.78 ALOX5 (0.60) ALOX5
SCHEMBL8409241 0.77 ALOX5 (0.55) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883106-A 5-lipoxygenase inhibitors PFIZER INC. (US) 1999-03-16 US disclosed