Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497458 | 0.83 | BRD4 (0.50) | BRD4PDK2CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL10203017 | 0.80 | BRD4 (0.55) | BRD4PDK2CYP4F2CYP4A11CYSLTR2 | |
| SCHEMBL6492212 | 0.77 | MAPT (0.46) | BRD4PDK2CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL12975430 | 0.76 | BRD4 (0.57) | BRD4PDK2CYSLTR2CYSLTR1LTA4H | |
| SCHEMBL16245544 | 0.76 | LTA4H (0.53) | BRD4PDK2CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL8409159 | 0.75 | LTA4H (0.39) | BRD4PDK2CYSLTR2CYSLTR1LTA4H | |
| SCHEMBL3433095 | 0.74 | BRD4 (0.46) | BRD4PDK2CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL17265678 | 0.74 | LTA4H (0.52) | BRD4PDK2CYSLTR2CYSLTR1LTA4H | |
| SCHEMBL5457249 | 0.74 | LTA4H (0.52) | BRD4PDK2CYSLTR2CYSLTR1LTA4H | |
| SCHEMBL4389091 | 0.73 | BRD4 (0.53) | BRD4PDK2CYP1A2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446173-B1 | Immunoassay for metolachlorine | NOVARTIS AG (CH) | 1999-07-14 | — | — | EP | disclosed |
| US-5576188-A | HYBRIDOMA CELL LINE WHICH PRODUCES A MONOCLONAL ANTIBODY HAVING SPECIFIED CHARACTERISTICS | CIBA-GEIGY CORPORATION (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0446173-A2 | Immunoassay for metolachlorine | CIBA-GEIGY AG (CH) | 1991-09-11 | — | — | EP | disclosed |