Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409294 | 0.75 | BRD4 (0.45) | LTA4HBRD4PDK2ALDH2MAOA | |
| SCHEMBL10203017 | 0.71 | BRD4 (0.55) | LTA4HBRD4PDK2ALDH2CNR2 | |
| SCHEMBL12975430 | 0.68 | BRD4 (0.57) | LTA4HBRD4PDK2CYSLTR2CYSLTR1 | |
| SCHEMBL6497458 | 0.67 | BRD4 (0.50) | LTA4HBRD4PDK2MCL1CYSLTR2 | |
| SCHEMBL23843414 | 0.67 | MAPT (0.49) | LTA4HBRD4MCL1ALDH1A1PDE3B | |
| SCHEMBL6491695 | 0.67 | HPGD (0.48) | LTA4HBRD4PDK2MCL1CYSLTR2 | |
| SCHEMBL3433095 | 0.67 | BRD4 (0.46) | LTA4HBRD4PDK2ALDH2CNR2 | |
| SCHEMBL23843497 | 0.67 | L3MBTL1 (0.44) | LTA4HBRD4PDK2MCL1CYSLTR2 | |
| SCHEMBL4389091 | 0.66 | BRD4 (0.53) | LTA4HBRD4PDK2CYSLTR2CYSLTR1 | |
| SCHEMBL19474670 | 0.65 | LTA4H (0.53) | LTA4HBRD4PDK2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446173-B1 | Immunoassay for metolachlorine | NOVARTIS AG (CH) | 1999-07-14 | — | — | EP | disclosed |
| US-5576188-A | HYBRIDOMA CELL LINE WHICH PRODUCES A MONOCLONAL ANTIBODY HAVING SPECIFIED CHARACTERISTICS | CIBA-GEIGY CORPORATION (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0446173-A2 | Immunoassay for metolachlorine | CIBA-GEIGY AG (CH) | 1991-09-11 | — | — | EP | disclosed |