SCHEMBL3433095

SCHEMBL3433095

CCOC(=O)CCCCCCOc1cc(Br)cc(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.46
DGKA P23743 1/20 0.46
FFAR1 O14842 1/20 0.46
PDK2 Q15119 1/20 0.46
ALDH2 P05091 2/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CYP3A4 P08684 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 1/20 0.44
CYSLTR2 Q9NS75 2/20 0.44
CYSLTR1 Q9Y271 2/20 0.44
LTA4H P09960 4/20 0.43
ALDH1A1 P00352 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CNR2 P34972 1/20 0.42
PLA2G2A P14555 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912241 0.91 DGKA (0.50) DGKACNR2PLA2G2AHDAC3HDAC4
SCHEMBL1284955 0.85 LTA4H (0.52) BRD4FFAR1PDK2CYSLTR2CYSLTR1
SCHEMBL1285180 0.85 LTA4H (0.52) BRD4FFAR1PDK2CYSLTR2CYSLTR1
SCHEMBL1285034 0.83 LTA4H (0.53) BRD4PDK2CYSLTR2CYSLTR1LTA4H
SCHEMBL2828409 0.79 PLA2G2A (0.47) BRD4TDP1PLA2G2A
SCHEMBL18205386 0.79 CYSLTR2 (0.47) BRD4DGKAFFAR1PDK2ALDH2
SCHEMBL987722 0.79 CYSLTR2 (0.56) BRD4PDK2CYSLTR2CYSLTR1ALDH1A1
SCHEMBL16607364 0.78 CYP1A2 (0.60) BRD4PDK2CYP3A4CYP1A2CYP2C19
SCHEMBL1194316 0.78 PDK2 (0.51) BRD4DGKAFFAR1PDK2ALDH2
SCHEMBL1171721 0.78 LTA4H (0.61) CYSLTR2CYSLTR1LTA4HTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639937-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2023-05-02 US disclosed
US-11639937-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2023-05-02 US disclosed
US-20170115298-A1 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LIMITED (GB) 2017-04-27 US disclosed
US-20170115298-A1 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LIMITED (GB) 2017-04-27 US disclosed
US-20160266132-A1 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LIMITED (GB) 2016-09-15 US disclosed
US-20160266132-A1 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LIMITED (GB) 2016-09-15 US disclosed
US-9383353-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN INC. (US) 2016-07-05 US disclosed
US-9383353-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN INC. (US) 2016-07-05 US disclosed
EP-2164988-B1 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN INC (US) 2016-02-17 EP disclosed
US-20150309016-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. 2015-10-29 US disclosed
US-8354239-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN, INC. (US) 2013-01-15 US disclosed
US-8158444-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN, INC. (GB) 2012-04-17 US disclosed
US-8158444-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN, INC. (GB) 2012-04-17 US disclosed
US-20120029155-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. (US) 2012-02-02 US disclosed
US-20120028828-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. (US) 2012-02-02 US disclosed
US-20120028828-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. (US) 2012-02-02 US disclosed
US-20120029155-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. (US) 2012-02-02 US disclosed
US-20080293164-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. 2008-11-27 US disclosed
US-20080293164-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. 2008-11-27 US disclosed
WO-2008100344-A2 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN INC. (US) 2008-08-21 WO disclosed