Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657702 | 0.93 | TDP1 (0.63) | LMNATDP1ESR1ESR2KMT2A | |
| SCHEMBL8658023 | 0.93 | TDP1 (0.58) | LMNATDP1ESR1ESR2KMT2A | |
| SCHEMBL14089605 | 0.81 | LMNA (0.46) | LMNATDP1ESR1ESR2KMT2A | |
| SCHEMBL8405675 | 0.80 | ALDH1A1 (0.51) | TDP1PLAUL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL7073708 | 0.79 | TDP1 (0.55) | LMNATDP1ESR1KMT2ASLC6A2 | |
| SCHEMBL7073022 | 0.79 | L3MBTL1 (0.51) | LMNATDP1ESR1KMT2ASLC6A2 | |
| SCHEMBL7078180 | 0.79 | TDP1 (0.51) | LMNATDP1ESR1ESR2KMT2A | |
| SCHEMBL8408253 | 0.79 | HRH3 (0.51) | LMNATDP1ESR1ESR2KMT2A | |
| SCHEMBL8655135 | 0.79 | TDP1 (0.41) | LMNATDP1ESR1ESR2KMT2A | |
| SCHEMBL8405334 | 0.78 | ALDH1A1 (0.47) | KMT2APLAUL3MBTL1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0722430-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996004228-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-02-15 | — | — | WO | disclosed |