Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408425 | 0.76 | SLC6A2 (0.39) | PDE5AKHKFLT3TYRO3MERTK | |
| SCHEMBL8917883 | 0.76 | EPHX2 (0.49) | KHKHRH4FLT3TYRO3MERTK | |
| SCHEMBL8406794 | 0.65 | SLC6A2 (0.40) | ADRA1DADRA1AADRA1BHTR1ASLC6A4 | |
| SCHEMBL28884912 | 0.65 | SIGMAR1 (0.42) | HTR2CHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8510998 | 0.64 | PDE5A (0.48) | PDE5AALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL1977303 | 0.64 | KDM4E (0.57) | PDE5AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3334093 | 0.64 | EPHX2 (0.51) | FLT3TYRO3MERTKGAS6PLD1 | |
| SCHEMBL9094827 | 0.63 | SCD (0.38) | ALDH1A1TSHRL3MBTL1KDM4EHPGD | |
| SCHEMBL8409833 | 0.63 | KHK (0.37) | KHKFLT3TYRO3MERTKGAS6 | |
| Hydrochloric Acid SCHEMBL8703350 | 0.63 | EPHX2 (0.50) | FLT3TYRO3MERTKGAS6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866589-A | Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1996018628-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |