Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.46 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792106 | 0.86 | GPR119 (0.46) | GPR119NR1D1POLBALDH1A1LMNA | |
| SCHEMBL8409617 | 0.85 | GPR119 (0.50) | GPR119POLBALDH1A1LMNAMAPT | |
| SCHEMBL8406542 | 0.85 | GPR119 (0.50) | GPR119POLBALDH1A1LMNAMAPT | |
| SCHEMBL8791648 | 0.78 | GPR119 (0.40) | GPR119 | |
| SCHEMBL20306597 | 0.78 | GPR119 (0.44) | GPR119NR1D1ALDH1A1LMNAMAPT | |
| SCHEMBL8791227 | 0.78 | CTSB (0.45) | ALDH1A1LMNAMAPT | |
| SCHEMBL1420930 | 0.77 | GPR119 (0.52) | GPR119POLBALDH1A1LMNAMAPT | |
| SCHEMBL30392767 | 0.76 | GPR119 (0.51) | GPR119POLBALDH1A1MET | |
| SCHEMBL14334348 | 0.76 | GPR119 (0.51) | GPR119POLBALDH1A1MET | |
| SCHEMBL14335007 | 0.75 | GPR119 (0.53) | GPR119POLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866589-A | Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0797576-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018628-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |