Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6169748 | 0.78 | KMT2A (0.49) | HDAC8F10KMT2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6164678 | 0.75 | HDAC8 (0.74) | HDAC8F10DPP8NLNACE | |
| SCHEMBL7650239 | 0.73 | KMT2A (0.56) | HDAC8F10DPP8KMT2AACE | |
| Hydrochloric Acid SCHEMBL6166952 | 0.70 | MC4R (0.44) | F10KMT2A | |
| Hydrochloric Acid SCHEMBL6161233 | 0.70 | MC4R (0.46) | F10KMT2A | |
| Hydrochloric Acid SCHEMBL6161239 | 0.70 | MC4R (0.46) | F10KMT2A | |
| SCHEMBL3280208 | 0.70 | KEAP1 (0.74) | CHRM4KMT2AHPGDKEAP1 | |
| SCHEMBL6168383 | 0.70 | MAPK1 (0.51) | F10KMT2ANPC1RAB9A | |
| SCHEMBL6168374 | 0.70 | MAPK1 (0.51) | F10KMT2ANPC1RAB9A | |
| SCHEMBL7647840 | 0.69 | ADORA1 (0.47) | HDAC8F10DPP8KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |