Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410015 | 0.89 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL8409987 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL11496541 | 0.80 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL8409761 | 0.79 | KDM4E (0.48) | MTNR1AMTNR1B | |
| SCHEMBL6081151 | 0.79 | CA1 (0.43) | MTNR1AMTNR1B | |
| SCHEMBL6081951 | 0.78 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL6081859 | 0.78 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL7658012 | 0.76 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL8410013 | 0.76 | KDM4E (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8407113 | 0.76 | KDM4E (0.46) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737670-B1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR (FR) | 1999-07-21 | — | — | EP | claimed |
| EP-0737670-B1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR (FR) | 1999-07-21 | — | — | EP | disclosed |
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |
| EP-0737670-A1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-10-16 | — | — | EP | disclosed |