SCHEMBL8410029

SCHEMBL8410029

N#Cc1cc(N[C]=O)ccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 8/20 0.51
GRM4 Q14833 1/20 0.49
IDO1 P14902 2/20 0.48
VCAM1 P19320 1/20 0.46
BLM P54132 1/20 0.40
WRN Q14191 1/20 0.40
PLA2G7 Q13093 1/20 0.37
TRPV4 Q9HBA0 1/20 0.36
ACACB O00763 1/20 0.35
ALDH1A1 P00352 1/20 0.34
ACLY P53396 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8410422 0.82 ALDH1A1 (0.44) SLC22A12IDO1ALDH1A1
SCHEMBL2095962 0.78 EPHX1 (0.52) IDO1ALDH1A1
SCHEMBL8410032 0.78 SLC22A12 (0.51) SLC22A12GRM4IDO1VCAM1BLM
SCHEMBL3833327 0.77 SLC22A12 (0.50) SLC22A12GRM4IDO1VCAM1BLM
SCHEMBL8343255 0.77 SLC22A12 (0.50) SLC22A12GRM4IDO1VCAM1BLM
SCHEMBL546976 0.74 SLC22A12 (0.55) SLC22A12PLA2G7
SCHEMBL1192659 0.74 ALDH1A1 (0.63) SLC22A12GRM4BLMWRNPLA2G7
SCHEMBL2093997 0.73 RAPGEF4 (0.42) GRM4IDO1BLMALDH1A1
SCHEMBL27397507 0.73 SLC22A12 (0.47) SLC22A12GRM4IDO1VCAM1BLM
SCHEMBL27902395 0.73 PGK1 (0.53) SLC22A12GRM4IDO1VCAM1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718277-B1 Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound FUJI PHOTO FILM CO LTD (JP) 1999-07-21 EP disclosed
EP-0718277-A1 Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound FUJI PHOTO FILM CO., LTD. (JP) 1996-06-26 EP disclosed