Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413099 | 0.89 | AGTR1 (0.76) | AGTR1AGTR2PPARG | |
| SCHEMBL9531605 | 0.83 | AGTR1 (0.56) | AGTR1AGTR2PPARGACHE | |
| SCHEMBL9531279 | 0.82 | AGTR1 (0.55) | AGTR1AGTR2PPARGACHE | |
| SCHEMBL9533553 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL9533449 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL9136699 | 0.80 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL9427397 | 0.78 | AGTR1 (0.61) | AGTR1AGTR2ACHE | |
| SCHEMBL9200201 | 0.78 | AGTR1 (0.52) | AGTR1AGTR2ACHE | |
| SCHEMBL8885452 | 0.77 | AGTR1 (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL8411067 | 0.77 | AGTR1 (0.54) | AGTR1AGTR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |