Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136699 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL9531605 | 0.79 | AGTR1 (0.56) | AGTR1AGTR2ACHE | |
| SCHEMBL9531279 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL9533449 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL9533553 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2ACHE | |
| SCHEMBL8410153 | 0.78 | AGTR1 (0.61) | AGTR1AGTR2ACHE | |
| SCHEMBL9427397 | 0.76 | AGTR1 (0.61) | AGTR1AGTR2ACHE | |
| SCHEMBL9844182 | 0.76 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL734 | 0.75 | AGTR2 (0.69) | AGTR1AGTR2 | |
| SCHEMBL462 | 0.75 | AGTR2 (0.80) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993003018-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1993-02-18 | — | — | WO | disclosed |