Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28996021 | 0.97 | KIF11 (0.43) | KIF11ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL12993225 | 0.88 | KIF11 (0.56) | KIF11ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL22952991 | 0.82 | KIF11 (0.60) | KIF11 | |
| SCHEMBL19059423 | 0.82 | KIF11 (0.60) | KIF11 | |
| SCHEMBL2319506 | 0.77 | ALDH1A1 (0.42) | KIF11ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL31090690 | 0.77 | KIF11 (0.44) | KIF11ALDH1A1KCNN4MAPK1TSHR | |
| SCHEMBL34009 | 0.75 | KIF11 (0.48) | KIF11ALDH1A1KCNN4MAPK1TSHR | |
| SCHEMBL7715769 | 0.75 | KIF11 (0.48) | KIF11ALDH1A1KCNN4MAPK1TSHR | |
| SCHEMBL13457486 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ESR1CYP3A4ESR2KCNN4 | |
| SCHEMBL17576267 | 0.74 | ALDH1A1 (0.46) | KIF11ALDH1A1ESR1CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276411-B | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2024-02-09 | — | — | CN | claimed |
| CN-114685608-A | Cyclic peptide compound containing trithioether bond or derivative thereof, and synthetic method and application thereof | 北京大学深圳研究生院 | 2022-07-01 | — | — | CN | claimed |
| CN-114276411-A | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2022-04-05 | — | — | CN | claimed |
| CN-110128666-B | Functionalized polyethyleneimine coated nano-gold particle composite material and preparation method thereof | 南京工业大学 | 2021-09-28 | — | — | CN | claimed |
| US-20170204102-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | THE REPUBLIC OF KOREA (MANAGEMENT: RURAL DEVELOPMENT ADMINISTRATION) (KR) | 2017-07-20 | — | — | US | claimed |
| US-20150119251-A1 | AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT | REPUBLIC OF KOREA (RURAL DEVELOPMENT ADMINISTRATION) (KR) | 2015-04-30 | — | — | US | claimed |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Kongju National University Industry- University Cooperation Foundation (KR) | 2013-07-25 | — | — | US | claimed |
| EP-2594134-A2 | AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Republic of Korea (Management: Rural Development Administration) (KR) | 2013-05-22 | — | — | EP | claimed |
| EP-0765307-B1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM IND CO LTD (KR) | 1999-10-20 | — | — | EP | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| EP-0765307-A1 | N ALPHA-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1997-04-02 | — | — | EP | claimed |
| US-5616788-A | FOR SOLID PHASE PEPTIDE SYNTHESIS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1997-04-01 | — | — | US | claimed |
| WO-1996025394-A1 | Nα-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1996-08-22 | — | — | WO | claimed |
| CN-114276411-B | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2024-02-09 | — | — | CN | disclosed |
| US-11807612-B2 | Heterocyclic compound and salt thereof, and luminescent substrate composition | THE UNIVERSITY OF ELECTRO-COMMUNICATIONS (JP) | 2023-11-07 | — | — | US | disclosed |
| CN-114685608-B | Cyclic peptide compound containing trithiophene bond or derivative thereof, synthesis method and application thereof | 北京大学深圳研究生院 | 2023-10-20 | — | — | CN | disclosed |
| US-4257947-A | INTERMEDIATES FOR ANTIBACTERIAL CEPHALOSPORINS | SMITHKLINE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4166816-A | CYCLIZATION | SMITHKLINE CORPORATION (US) | 1979-09-04 | — | — | US | disclosed |
| US-4103086-A | 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives | SMITHKLINE CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204102-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | HDHD5, DAZAP1, MAPKAPK5 | KIF11 1543/4885ALDH1A1 3568/4885ESR1 4833/4885 |
| US-20150119251-A1 | AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT | PEPD, DNPEP, DPP7 | KIF11 4255/4885ALDH1A1 4580/4885ESR1 4764/4885 |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | HDHD5, DAZAP1, MAPKAPK5 | KIF11 1543/4885ALDH1A1 3568/4885ESR1 4833/4885 |
| US-11807612-B2 | Heterocyclic compound and salt thereof, and luminescent substrate composition | RXFP4, NR2E3, ARRB1 | KIF11 4733/4885ALDH1A1 2259/4885ESR1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.