Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801004 | 0.83 | CYP1A2 (0.45) | GRM2CYP1A2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4800998 | 0.83 | CYP1A2 (0.45) | GRM2CYP1A2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8726233 | 0.81 | HSD11B1 (0.40) | CYP1A2SLC6A4SLC6A3SLC6A2HSD11B1 | |
| SCHEMBL7507869 | 0.81 | MEN1 (0.47) | GRM2HSD11B1MAPTTP53POLB | |
| SCHEMBL9180980 | 0.79 | SLC6A3 (0.40) | GRM2CYP1A2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7511127 | 0.79 | MEN1 (0.48) | HSD11B1MAPTTP53POLBCYP3A4 | |
| SCHEMBL11231469 | 0.77 | SLC6A4 (0.40) | GRM2SLC6A4TP53 | |
| SCHEMBL7757750 | 0.75 | MAOB (0.48) | GRM2SLC6A4SLC6A3SLC6A2PSMD14 | |
| SCHEMBL11298227 | 0.75 | SPHK1 (0.48) | GRM2MAPTGAA | |
| SCHEMBL11298231 | 0.75 | SPHK1 (0.48) | GRM2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394417-B2 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0366985-B1 | Super twist liquid crystal display | MERCK PATENT GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |