Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727353 | 0.92 | HSD11B1 (0.43) | HSD11B1MEN1KMT2AKCNH2CACNA1I | |
| SCHEMBL8726981 | 0.88 | SLC6A4 (0.39) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8729401 | 0.86 | SLC6A4 (0.43) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8410642 | 0.81 | GRM2 (0.39) | HSD11B1SLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL7511127 | 0.81 | MEN1 (0.48) | HSD11B1MEN1KMT2AKCNH2CACNA1I | |
| SCHEMBL7507869 | 0.80 | MEN1 (0.47) | HSD11B1MEN1KMT2AKCNH2CACNA1I | |
| SCHEMBL8725824 | 0.80 | SLC6A4 (0.39) | HSD11B1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL9797584 | 0.79 | CYP1A2 (0.50) | MEN1KMT2ATP53MAPTCYP1A2 | |
| SCHEMBL10435336 | 0.79 | CYP1A2 (0.44) | MEN1KMT2ATP53MAPTGPR119 | |
| SCHEMBL8729811 | 0.78 | SLC6A4 (0.43) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |