Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268003 | 0.79 | CA12 (0.36) | CA12CA1CA9DRD3 | |
| SCHEMBL8408803 | 0.78 | KCNH2 (0.44) | — | |
| SCHEMBL7802457 | 0.77 | POLB (0.33) | HCAR1CA12CA1CA9PARP1 | |
| SCHEMBL9301537 | 0.74 | DRD3 (0.35) | CA12CA1CA9DRD3 | |
| SCHEMBL9940281 | 0.74 | TSHR (0.41) | PARP1 | |
| SCHEMBL29428973 | 0.69 | AKR1C3 (0.42) | PARP1 | |
| SCHEMBL28806180 | 0.68 | CYP19A1 (0.32) | CA12CA1CA9 | |
| SCHEMBL30762367 | 0.68 | KDM4E (0.30) | — | |
| SCHEMBL30762452 | 0.67 | OPRL1 (0.31) | — | |
| SCHEMBL8410986 | 0.67 | S1PR5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |