Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 14/20 | 0.43 |
| ▸ | CASP6 | P55212 | 11/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 11/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411108 | 0.86 | CASP1 (0.62) | CASP1CASP3 | |
| SCHEMBL8414714 | 0.82 | CASP1 (0.52) | CASP1CASP3CASP6CASP8L3MBTL1 | |
| SCHEMBL8519168 | 0.78 | CASP1 (0.47) | CASP1CASP3 | |
| SCHEMBL6830886 | 0.78 | CASP3 (0.49) | CASP1CASP3CASP6CASP8 | |
| SCHEMBL7425226 | 0.77 | CASP1 (0.65) | CASP1CASP3CASP6CASP8 | |
| SCHEMBL7414180 | 0.77 | CASP1 (0.57) | CASP1CASP3CASP6CASP8 | |
| SCHEMBL8410793 | 0.77 | CASP1 (0.55) | CASP1CASP3CASP6CASP8L3MBTL1 | |
| SCHEMBL8411135 | 0.76 | CASP1 (0.79) | CASP1 | |
| SCHEMBL8410991 | 0.76 | CASP1 (0.49) | CASP1L3MBTL1 | |
| SCHEMBL8520531 | 0.76 | CASP1 (0.47) | CASP1CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932598-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016502-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |