Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412352 | 0.90 | CYP2D6 (0.47) | CYP2C19CYP2D6HSD11B1LMNAKMT2A | |
| SCHEMBL8413001 | 0.84 | L3MBTL1 (0.41) | CYP2C19CYP2D6LMNAKMT2AALDH1A1 | |
| SCHEMBL8412311 | 0.82 | HSD11B1 (0.47) | CYP2C19CYP2D6HSD11B1LMNAKMT2A | |
| SCHEMBL8413904 | 0.81 | CYP2C19 (0.46) | CYP2C19CYP2D6HSD11B1LMNAKMT2A | |
| SCHEMBL8409854 | 0.80 | CYP2C19 (0.45) | CYP2C19CYP2D6HSD11B1LMNAKMT2A | |
| SCHEMBL8413553 | 0.80 | HSD11B1 (0.45) | CYP2C19CYP2D6HSD11B1LMNAKMT2A | |
| SCHEMBL8412314 | 0.79 | CYP2D6 (0.44) | CYP2C19CYP2D6HSD11B1LMNAKMT2A | |
| SCHEMBL8410572 | 0.79 | KMT2A (0.42) | CYP2C19KMT2AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL8413423 | 0.79 | HTR7 (0.43) | KMT2AMEN1HTR2A | |
| SCHEMBL8410851 | 0.78 | SLC18A3 (0.47) | CYP2C19CYP2D6HSD11B1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |