SCHEMBL8411539

SCHEMBL8411539

COC(OC)C1CCCO1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 8/20 0.36
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
GAA P10253 1/20 0.31
POLB P06746 2/20 0.30
HSD17B10 Q99714 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5475612 0.79
SCHEMBL17487296 0.77
SCHEMBL15277276 0.77
SCHEMBL28065790 0.77
SCHEMBL14764021 0.76 ALDH1A1 (0.36) SLC6A3ALDH1A1HPGDSMN1; SMN2
SCHEMBL28058320 0.73 ALDH1A1 (0.32) ALDH1A1HPGDSMN1; SMN2HSD17B10RAB9A
SCHEMBL5560813 0.73 SLC6A3 (0.32) SLC6A3
SCHEMBL7936027 0.73 SLC6A3 (0.32) SLC6A3
SCHEMBL1188560 0.72 HPGD (0.38) ALDH1A1HPGDSMN1; SMN2L3MBTL1GAA
SCHEMBL12119805 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461666-B A kind of preparation method of 2 substituted tetrahydrofuran class compound 华东师范大学 2018-03-13 CN disclosed
CN-105461666-B A kind of preparation method of 2 substituted tetrahydrofuran class compound 华东师范大学 2018-03-13 CN disclosed
CN-105461666-A Preparation method of 2-substituted tetrahydrofuran compounds UNIV EAST CHINA NORMAL 2016-04-06 CN disclosed
CN-105461666-A Preparation method of 2-substituted tetrahydrofuran compounds UNIV EAST CHINA NORMAL 2016-04-06 CN disclosed
EP-0934294-A1 PREPARATION OF 3-METHYLTETRAHYDROFURAN FROM 2,3-DIHYDROFURAN EASTMAN CHEMICAL COMPANY (US) 1999-08-11 EP disclosed
WO-1998017658-A1 PREPARATION OF 3-METHYLTETRAHYDROFURAN FROM 2,3-DIHYDROFURAN EASTMAN CHEMICAL COMPANY (US) 1998-04-30 WO disclosed
CN-1009648-B Process for producing styrene-butadiene random copolymer INST OF YANSHAN PETROCHEMICAL (CN) 1990-09-19 CN disclosed