Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058219 | 0.89 | SMN1; SMN2 (0.39) | ALDH1A1KMT2ARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL14764021 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29184202 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL29184201 | 0.80 | HPGD (0.33) | ALDH1A1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL4920076 | 0.78 | — | — | |
| SCHEMBL14309115 | 0.75 | SLC6A3 (0.32) | — | |
| SCHEMBL10306297 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1KMT2AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8411539 | 0.73 | SLC6A3 (0.36) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL8386920 | 0.73 | THRB (0.33) | — | |
| SCHEMBL8195821 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461666-B | A kind of preparation method of 2 substituted tetrahydrofuran class compound | 华东师范大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-105461666-A | Preparation method of 2-substituted tetrahydrofuran compounds | UNIV EAST CHINA NORMAL | 2016-04-06 | — | — | CN | disclosed |
| CN-105461666-A | Preparation method of 2-substituted tetrahydrofuran compounds | UNIV EAST CHINA NORMAL | 2016-04-06 | — | — | CN | disclosed |