Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600035 | 0.86 | FFAR1 (0.50) | FFAR1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL8110686 | 0.83 | NSD2 (0.56) | FFAR1NSD2MAOAMAOBCYP19A1 | |
| SCHEMBL27618580 | 0.78 | LOXL2 (0.57) | FFAR1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL8411721 | 0.77 | MAOA (0.58) | FFAR1NSD2MAOAMAOBCYP19A1 | |
| SCHEMBL7935598 | 0.73 | MAOA (0.61) | NSD2MAOAMAOBCYP19A1VNN1 | |
| SCHEMBL10671478 | 0.73 | GSK3B (0.59) | FFAR1NSD2EPHX2KCNJ1KCNH2 | |
| SCHEMBL17857729 | 0.73 | TSHR (0.62) | NSD2MAOAMAOBCYP19A1KDM4E | |
| SCHEMBL13263434 | 0.72 | FFAR1 (0.47) | FFAR1MAOAMAOBKCNJ1KCNH2 | |
| SCHEMBL2339110 | 0.72 | CYP2A6 (0.52) | FFAR1MAOAMAOBKCNJ1KCNH2 | |
| SCHEMBL1337387 | 0.72 | FFAR1 (0.69) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962495-A | ESTROGEN SENSITIVE DISEASES; BREAST CANCER; PROSTATE TUMORS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 1999-10-05 | — | — | US | disclosed |
| US-5703109-A | CYANOPHENYL-1,2,4-TRIAZOLE DERIVATIVE | Oy, Orion-yhtyma (FI) | 1997-12-30 | — | — | US | disclosed |