Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 1/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671478 | 0.92 | GSK3B (0.59) | NSD2FFAR1RAB9ANPC1GSK3B | |
| SCHEMBL10559396 | 0.87 | NPC1 (0.67) | FFAR1RAB9ANPC1SLC5A1SLC5A2 | |
| SCHEMBL9641209 | 0.84 | HSD11B1 (0.56) | FFAR1RAB9ANPC1GSK3BMAOA | |
| SCHEMBL8411540 | 0.83 | FFAR1 (0.51) | NSD2FFAR1VNN1MAOAMAOB | |
| SCHEMBL19367865 | 0.82 | GSK3B (0.59) | NSD2RAB9ANPC1GSK3BVNN1 | |
| SCHEMBL3738077 | 0.80 | FFAR1 (0.46) | NSD2FFAR1RAB9AGSK3BVNN1 | |
| SCHEMBL6202254 | 0.79 | TP53 (0.59) | RAB9ANPC1GSK3BSLC5A1SLC5A2 | |
| SCHEMBL11612967 | 0.79 | HTR7 (0.59) | FFAR1RAB9ANPC1SLC5A1SLC5A2 | |
| SCHEMBL20262696 | 0.79 | NPC1 (0.56) | FFAR1RAB9ANPC1GSK3BSLC5A1 | |
| SCHEMBL6158144 | 0.79 | NPC1 (0.56) | FFAR1RAB9ANPC1SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-B1 | SELECTIVE AROMATASE INHIBITING COMPOUNDS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 2000-07-19 | — | — | EP | disclosed |
| US-5962495-A | ESTROGEN SENSITIVE DISEASES; BREAST CANCER; PROSTATE TUMORS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 1999-10-05 | — | — | US | disclosed |
| US-5703109-A | CYANOPHENYL-1,2,4-TRIAZOLE DERIVATIVE | Oy, Orion-yhtyma (FI) | 1997-12-30 | — | — | US | disclosed |
| EP-0476944-B1 | Aromatase inhibiting 4(5)-imidazoles | ORION YHTYMAE OY (FI) | 1995-11-15 | — | — | EP | disclosed |
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013645-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | Orion-Yhtymä Oy (FI) | 1994-06-23 | — | — | WO | disclosed |
| EP-0476944-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1992-03-25 | — | — | EP | disclosed |