Acrylic Acid

Acrylic Acid

SCHEMBL8411601

C=C=COC(=O)C=C.C=CC(=O)O

nearest known ligand 0.46

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
TSHR P16473 5/20 0.32
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL874903 0.93
Itaconate SCHEMBL8385423 0.78 ALOX15 (0.56) HSD17B10ALOX15
Acrylic Acid SCHEMBL1531352 0.75 LMNA (0.56) LMNATSHRALDH1A1TP53HIF1A
SCHEMBL3434253 0.72
Acrylic Acid SCHEMBL3446512 0.71
Acrylic Acid SCHEMBL30300770 0.71 LMNA (0.77) LMNATSHRALDH1A1TP53HSD17B10
Acrylic Acid SCHEMBL1778362 0.71 LMNA (0.77) LMNATSHRALDH1A1TP53HSD17B10
SCHEMBL10390321 0.70 KEAP1 (0.31)
Acrylic Acid SCHEMBL21680281 0.70 LMNA (0.48) LMNATSHRALDH1A1TP53HIF1A
SCHEMBL1782680 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587390-B1 A silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1999-08-04 EP disclosed
US-5681688-A LAYER OF SILVER HALIDE EMULSION, EMULSION PROTECTIVE LAYER, BACKING LAYER OR BACKING PROTECTIVE LAYER CONTAINS LATEX OF COPOLYMER KONICA CORPORATION (JP) 1997-10-28 US disclosed
EP-0317247-B1 Silver halide photographic light-sensitive material and the method of preparing the same KONISHIROKU PHOTO IND (JP) 1994-11-09 EP disclosed
EP-0587390-A2 A silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1994-03-16 EP disclosed
US-4946769-A HEATING, COATING, COOLING AND GELATION OF A SILVER HALIDE EMULSION AND GELATIN ON A NON-LIGHT SENSITIVE LAYER KONICA CORPORATION (JP) 1990-08-07 US disclosed
EP-0317247-A2 Silver halide photographic light-sensitive material and the method of preparing the same KONICA CORPORATION (JP) 1989-05-24 EP disclosed