Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.65 |
| ▸ | FAAH | O00519 | 6/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18814236 | 0.81 | MGLL (0.68) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL18661434 | 0.80 | MGLL (0.75) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL3482931 | 0.79 | MGLL (1.00) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL1683222 | 0.76 | MGLL (0.73) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL31664393 | 0.76 | MGLL (0.73) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL29353761 | 0.73 | MGLL (0.56) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL331574 | 0.73 | MGLL (0.56) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL17208730 | 0.73 | MGLL (0.69) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL19508523 | 0.73 | MGLL (0.69) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL18469620 | 0.73 | MGLL (0.69) | MGLLFAAHHSP90AA1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934081-A2 | ANTINEOPLASTIC CONJUGATES OF TRANSFERRIN, ALBUMIN AND POLYETHYLENE GLYCOL | Kratz, Felix (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998010794-A2 | ANTINEOPLASTIC CONJUGATES OF TRANSFERRIN, ALBUMIN AND POLYETHYLENE GLYCOL | KRATZ FELIX (DE) | 1998-03-19 | — | — | WO | disclosed |