Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 15/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415413 | 0.90 | TSHR (0.35) | ALDH1A1HPGDSMN1; SMN2P2RX7MAPT | |
| SCHEMBL8411821 | 0.81 | ALDH1A1 (0.31) | ALDH1A1HPGD | |
| SCHEMBL4261100 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2P2RX7ABCB1 | |
| SCHEMBL7895445 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2P2RX7LMNA | |
| SCHEMBL7599531 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2P2RX7EPHX2 | |
| SCHEMBL7597337 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2P2RX7EPHX2 | |
| SCHEMBL7602216 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2P2RX7 | |
| SCHEMBL7599406 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2P2RX7 | |
| SCHEMBL7597275 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2P2RX7 | |
| SCHEMBL8413766 | 0.69 | IRAK4 (0.42) | P2RX7LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934257-A1 | SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998002413-A1 | SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-01-22 | — | — | WO | claimed |
| EP-0934257-A1 | SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998002413-A1 | SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-01-22 | — | — | WO | disclosed |