Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136095 | 0.85 | ALOX15 (0.50) | HPGDACEPTPN1ITGB3ITGA2B | |
| SCHEMBL27001678 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BALOX15 | |
| SCHEMBL27131690 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8411377 | 0.81 | UBASH3B (0.45) | HPGDACEPTPN1CA2GPR132 | |
| SCHEMBL8409073 | 0.81 | HPGD (0.77) | HPGDACEPTPN1PTPN2CDC25B | |
| SCHEMBL7834954 | 0.81 | HPGD (0.77) | HPGDACEPTPN1PTPN2CDC25B | |
| SCHEMBL11888462 | 0.79 | ACE (0.54) | ACEPTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL11888479 | 0.79 | ACE (0.54) | ACEPTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL20791672 | 0.77 | ALOX15 (0.49) | HPGDACEPTPN1ALOX15ALOX12 | |
| SCHEMBL20791671 | 0.77 | ALOX15 (0.49) | HPGDACEPTPN1ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |