Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410142 | 0.90 | TACR1 (0.52) | TACR1MC4RMC5RMAPT | |
| SCHEMBL8410099 | 0.89 | MC4R (0.43) | TACR1MC4RMC5RMAPT | |
| SCHEMBL6166209 | 0.87 | MAPK1 (0.49) | NR1H2 | |
| SCHEMBL6166213 | 0.87 | MAPK1 (0.49) | NR1H2 | |
| SCHEMBL8412366 | 0.83 | HDAC3 (0.51) | TACR1NR1H2 | |
| SCHEMBL6161717 | 0.78 | MAPK1 (0.50) | — | |
| SCHEMBL6161724 | 0.78 | MAPK1 (0.50) | — | |
| SCHEMBL6168374 | 0.77 | MAPK1 (0.51) | TACR1 | |
| SCHEMBL6168383 | 0.77 | MAPK1 (0.51) | TACR1 | |
| SCHEMBL6163821 | 0.76 | MAPK1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |