Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804056 | 0.83 | FBP1 (0.44) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| Fluorobenzene SCHEMBL10780996 | 0.82 | FBP1 (0.44) | FBP1ALDH1A1MMP8MEN1KMT2A | |
| SCHEMBL17674102 | 0.80 | ALDH1A1 (0.40) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL11803604 | 0.79 | FBP1 (0.39) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL5528368 | 0.77 | FBP1 (0.37) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL7620521 | 0.77 | FBP1 (0.38) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL28272742 | 0.77 | CYP4F2 (0.39) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL8398253 | 0.77 | FBP1 (0.40) | FBP1ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL28215158 | 0.75 | CYP4F2 (0.46) | FBP1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL8400791 | 0.75 | PKM (0.43) | FBP1CYP4F2CYP4A11ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811602-B1 | Process for the preparation of salts of the aminomalonic ester | HUELS CHEMISCHE WERKE AG (DE) | 1999-07-28 | — | — | EP | disclosed |
| US-5847197-A | Process for the preparation of aminomalonic acid ester salts | HUELS AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0811602-A1 | Process for the preparation of salts of the aminomalonic ester | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |