Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414339 | 0.86 | PPARG (0.34) | PPARGPPARAPTGIR | |
| SCHEMBL8414354 | 0.83 | RXRA (0.39) | PPARGPPARAPTGIRLMNA | |
| SCHEMBL8414123 | 0.76 | C3AR1 (0.33) | PTGIR | |
| SCHEMBL8410905 | 0.76 | PTGIR (0.49) | PTGIR | |
| SCHEMBL8414351 | 0.75 | PTGIR (0.30) | PTGIR | |
| SCHEMBL8411289 | 0.71 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL8411195 | 0.71 | PTGIR (0.45) | PTGIR | |
| SCHEMBL8414269 | 0.70 | PPARG (0.32) | PPARGPPARA | |
| SCHEMBL8411446 | 0.69 | PTGIR (0.33) | PTGIR | |
| SCHEMBL8411148 | 0.68 | RXRA (0.39) | PPARGPPARAPTGIRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |